Menthol is a natural organic compound derived mainly from peppermint oil and other mint plants, characteristic cooling sensation on the skin and mucous membranes. It can be obtained by extracting mint oils or produced synthetically in the laboratory. What is menthol Menthol is a clear, colorless crystalline substance with a strong, minty smell and taste. It can exist in different stereoisomers, the most common natural form being (–)-menthol (l‑menthol), while the synthetic version is often a racemic mixture (±)-menthol. How it works in the body Menthol creates a cooling sensation because it activates cold receptors on the skin and mucous membranes, primarily the TRPM8 ion channels (and partly TRPA1), which send “cold” signals to sensory nerves. This stimulation produces a soothing, mildly local‑anesthetic effect and can help relieve mild itching, pain, and airway irritation. Main uses Skin and muscle care: Used in creams, balms, or gels for muscle pain, soreness, and mild h...
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